Vergil is encountered as the level boss 3 times. First fight is in Mission 7 before Dante's DT Awakening. Then Mission 13 for the runback with Beo. Finally, serves as the last boss in Mission 20 armed with FE. Dante keeps A&R against him till the last encounter while Vergil has the best weapon against Vante right off the bat which is Beo.
Vergil/Vante 1 uses Yam only. Shotgun cancel or PS is usually used during sheating before Meleeing. Players has to make sure to leave leave him some room behind him so he won't teleport.
It's possible to loop **Vergil** by clashing with his Upper Slash to keep the DPS going with the correct timing of Aerial Cross and Air Guard.
The same can be said with Vante by either Helm Breaker or Aerial Rave. There is a risk still on bad positioning that causes Vergil to teleport or rapid slash.
Example of Vergil loop with Dante. 13 Reb strikes is advised when learning this game.
Example of Vante loop with Vergil. Be wary of PS timing on when to shoot.
Vergil/Vante 2 uses Beo. Once his health below 40%, he combines his arsenal with Yam. The goal of this fight is to skip his DT Phase.
Standard Vergil 2 with Dante. Aerial Cross and No Devil Star method is not recommended due to the lack of consistency.
Usual Vante 2 with Vergil. Most important part is not to drop JC's excessively during DTE and keep tack of your JC count.
Vergil/Vante 3 uses FE and Yam right off the bat. The big danger of this fight is his Super DT Phase and players have to avoid triggering this by killing him at certain HP threshold. This fight also has RNG layers when it comes to a good fight refer to Best Segemented time.
Vergil 3 example with Dante. Hit confirming with Beo 1 or 1,2 hits helps the consistency for Killer Bee JC's.
Vante 3 example with Vergil. You can choose to not DTE at the end and just DT JC but that also means none of your StarFall JC should be dropped which would cause a chance of failing Super DT skip.
Same concept but, you need to watch out his attacks. Especially his PS since they insta-kill.
It's good to check the Frequently Asked Questions (FAQ) if you have general questions regarding the bosses.