DmC and DMC5 are the only games that breaks the tradition of Normal difficulty being the main category. Devil Hunter does not change the AI nor the spawns like DMC1. All it does is increase health of everything. Therefore, community came into conclusion that Human simply has better pacing and strategies for this run overall.
This because your style meter lacks S rank, which makes the character stronger and increases the damage by 20%.
The Warehouse Fight Skip prevents the fight from ending even if you defeat both of them, and resetting fixes that.
Depends on the player's comfortability, some factors are:
Yes, the game only allows you to play Human, Devil Hunter or Nephilim from a fresh file.
Without customizable turbo (usually only on turbo controllers instead of back attachments), turbo for infinite climb is totally useless. If you do this trick at max speed all the time, you will never ascend past like, triple jump height.
This means you will have to look at controllers or back attachments with customizable turbo settings. Magic Pack PS4 Controller Encoder (by MAYFLASH) is one good example.
At the moment, only original game has it due it's recent OoB findings. These skips are yet to be tested and applied in Definitive Edition.
The original design for the DT had it draining more if you were on the ground, and less if you were in the air. This idea is scrapped but never fixed the extra drain, which is why DT drains so fast in this game.