Malphas is a one time encounter as the level boss of Mission 15.
Strategy
This fight is exactly the same as Qliphoth Roots however, this time you are dealing with more active enemy.
If you ever get hit from this boss and trigger the cutscene where V throws a Ragtime. All the detonated Overture will be gone.
Devil Hunter requires a good Exceeds of Aerial Combo in a spot where RQ recovers fast. This because, if you hit the magicians then your attacks will be much slower.
Do not deal damage against Malphas too hard at the start. This will ruin her behaviour and will teleport more often.
Vergil trivializes this fight with JJC. At the same time, make sure to freeze the boss with Heavy Rain Blades before summoning DG. Because NG+ has more DT-Gauge, you can add Blistering Blades for extra damage.
NG+ Nero uses 4 Gerberas directly against the the magicians because his DT Bringer Claw can knock down the boss very fast with one Slow World
It's worth a shot to attempt for Sequential Judgement Cuts as it saves more time.
Special Edition may affect his behaviour differently due to turbo feature.